Potential Combination Therapy For Metastatic Breast Cancer

Background

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  • A global pharmaceutical client was in the process of developing a new combination therapy for HR+/HER2+ metastatic breast cancer (MBC) and required a thorough understanding of the dynamics across different patient groups

Objective

  • To evaluate the effectiveness, safety, and patient outcomes of HR+/HER2+ MBC therapy, a novel targeted treatment for advanced cancer, through secondary research methods

Solution

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  • Conducted comprehensive desk research, analyzing data from sources including:
    • –  Academic databases (e.g., PubMed, Cochrane Library, Embase, Scopus)
    • –  Peer-reviewed oncology journals
    • –  Government health agencies (e.g., NCI, FDA)
    • –  Conference proceedings (e.g., ASCO, ESMO)
    • –  Industry and pharmaceutical company reports
  • To address any gaps and corroborate the information derived from secondary sources, we conducted expert interviews with oncologists and patient groups to validate and gain a deeper understanding of the current landscape of breast cancer therapies

Impact

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  • This approach revealed significant insights into the acceptance rate of the new combination therapy, influenced by the gathered evidence
  • These findings helped the pharmaceutical company identify crucial insights to determine the next steps for ensuring optimal patient support and drug safety. The research expedited decision-making and provided a clear direction for improving the therapy